Nearly 90% of Americans at risk of silent disease — here's what to know

January 25, 2026 - 20:59

A new study presents a complex picture of American heart health, indicating that nearly 90% of the adult population carries some risk for cardiovascular-kidney-metabolic (CKM) syndrome, a silent and interconnected set of conditions affecting the heart, kidneys, and metabolism. This condition often develops without obvious symptoms but significantly elevates the risk for major cardiac events.

The research highlights a concerning trend: while deaths from heart attacks have declined, fatalities from strokes are now rising among younger adults aged 35 to 64. This shift underscores the stealthy nature of these systemic risks, which include factors like high blood pressure, elevated blood sugar, excess body fat, and kidney disease.

Medical experts emphasize that the widespread prevalence of these risk factors is a critical public health issue. The interconnectedness of the heart, kidneys, and metabolic system means that a problem in one area can silently strain the others. The findings serve as a crucial reminder for individuals to discuss comprehensive screening with their healthcare providers, even in the absence of symptoms, to address these risks early.